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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $480 | Backorder | |
1 mL x 10 mM (in DMSO) | $490 | Backorder |
Description | Jatropholone B shows antiproliferative activity against cancer cell lines. It also has gastroprotective activity in preventing the gastric lesions in mice. |
In vitro | The cells used comprised normal lung fibroblasts (MRC-5), gastric adenocarcinoma (AGS), leukemia (HL-60), lung cancer (SK-MES-1), and bladder carcinoma (J82). Jatropholone A ( 1) was inactive against all the tumor cell lines; however, its acetylation rendered a compound with antiproliferative activity. The epimeric Jatropholone B ( 8) was active against all the cancer cell lines, and its derivatives presented different effects on the selected cell lines. |
Molecular Weight | 296.4 |
Formula | C20H24O2 |
Cas No. | 71386-38-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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